We profiled both T-cell and macrophage populationsn in tissue resection specimens from untreated patients with either BRCA-WT or BRCA1-associated TNBC.
t-CyCIF was performed on formalin-fixed, paraffin-embedded (FFPE) tumors. Entire tissue sections were analyzed yielding ~ 2 x 105 segmented and profiled cells per specimen.
This dataset is from a BRCA1-associated TNBC specimen. Images from other specimens are listed here. A side-by-side comparison of BRCA-WT and BRCA1-associated TNBC can be found here.
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