We profiled both T-cell and macrophage populationsn in tissue resection specimens from untreated patients with either BRCA-WT or BRCA1-associated TNBC.

t-CyCIF was performed on formalin-fixed, paraffin-embedded (FFPE) tumors. Entire tissue sections were analyzed yielding ~ 2 x 10⁵ segmented and profiled cells per specimen.

This dataset is from a BRCA1-associated TNBC specimen. Images from other specimens are listed here. A side-by-side comparison of BRCA-WT and BRCA1-associated TNBC can be found here.