Tumor associated macrophage phenotype and function is directly regulated by PARP inhibition and can be harnessed to overcome PARP-inhibitor resistance in BRCA-mutant triple negative breast cancer

Anita K. Mehta, Emily M. Cheney, Jessica A. Castrillon, Jia-Ren Lin, Mateus de Oliveira Taveira, Christina A. Hartl, Nathan T. Johnson, , William M. Oldham, Marian Kalocsay, Matthew J. Berberich, Sarah A. Boswell, Constantia Pantelidou, Brett P. Gross, Shawn Johnson, Deborah A. Dillon, Mikel Lipschitz, Scott Rodig, Sandro Santagata, Judy E. Garber, Nadine Tung, Elizabeth A. Mittendorf, Geoffrey I. Shapiro, Peter K. Sorger, Jennifer L. Guerriero

Dataset

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BRCA-WT vs BRCA1-associated TNBC

CyCIF image